Dr. Isaac Golden’s Homeoprophylaxis Research Overview

Homeoprophylaxis – A Proven Alternative to Vaccination by Dr Isaac Golden
As it appeared in Nourished Magazine, December 2008

I prepared my first formal program of homoeopathic remedies to prevent infectious diseases in 1986 (1). In the following 20+ years, tens of thousands of Australian children have been immunised homoeopathically – a method called homoeoprophylaxis (HP) – using programs from myself as well as other practitioners across the country. The method itself is over 200 years old, and has considerable clinical and research experience to support its claims.
In 2004, I integrated 18 years of data collection from parents of children using my program with 4 years of doctoral research at Swinburne University in Melbourne. The purpose of this article is to share with you the findings of this and other research into the effectiveness and safety of HP.

Background
The use of HP was first described by Dr Samuel Hahnemann, the founder of homoeopathy, in 1801(2). He used the remedy Belladonna 30 to successfully treat patients with the disease Scarlet Fever, but fortuitously found that the remedy also helped to prevent the disease. He then used HP to prevent such diseases as Cholera and Typhoid. In the decades following, many leading homoeopaths used HP to prevent a variety of infectious diseases, mainly in acute epidemic situations (3).
The largest trial of the short-term use of HP was against an outbreak of Meningococcal disease in Brazil. The researchers gave 65,826 children the homoeopathic remedy Meningococcinum. Another 23,539 were not protected. The effectiveness of HP after 6 months was 95%, and after a 12 months follow-up was 91% (4).
Whilst many homoeopaths also use HP for long-term prevention (mainly in Australia and the Indian subcontinent), there had been very little formal statistical research into the long-term use of HP prior to 1985. The data I have collected since that time provides a useful guide as to the effectiveness and safety of long-term HP. It confirms that the findings regarding epidemic use also extend to long-term use, with an average effectiveness of around 90%, and a very high level of safety. These findings are presented below.

The Effectiveness of Homoeoprophylaxis
As mentioned above, we have a considerable amount of clinical evidence showing that HP provides a high level of protection against targeted infectious diseases. This is supported by a small number of statistical trials which are summarised in Table 1 below. These show an average effectiveness of around 90%, which certainly is comparable to measures of vaccine effectiveness, which range from 70% to 99%, depending on the individual vaccine, and the type
of trial used to measure efficacy (real-world experiences show lower rates than clinical trials) (5).
These figures confirm that no method of disease prevention is ever 100% effective.
No statistical study is ever perfect, and of course the reliability of my data is open to question. So as part of my Swinburne research, I applied seven statistical tests to validate the long-term data I have been collecting since 1985. These are described in detail elsewhere (6), and they did show a high level of reliability. For example, my single figure measure of long-term HP effectiveness was 90.4%, with 95% confidence limits of 87.6% – 93.2% (i.e. it can be stated with 95% confidence that the efficacy lies between 87.6% AND 93.2%), a very strong result.

Table 1: The Effectiveness of HP – Statistical Trials in Humans

Year Researcher* Numbers of Participants Length of Survey Effectiveness %
1907 Eaton 2,806 < 1 year 97.5
1950 Taylor-Smith 82 (12 definitely exposed) < 1 year 100.0
1963 Gutman 385 < 1 year 86.0
1974 Castro & Nogeira HP 18,000Not HP 6,340 3 months 86.1
1987 English 694 2 years 87.0 – 91.5
1987 Fox 61 5 years 82.0 – 95.0
1998 Mroninski et al HP 65,826Not HP 23,539 6 months12 months 95.091.0
1997 Golden 593 children1,305 questionnaires 10 years 88.8
2004 Golden 1,159 children2,342 questionnaires 15 years 90.4
*References for these studies may be found in Vaccination and Homoeoprophylaxis – A Review of Risks and Alternatives, 6th edition (7)

So those in pharmaceutical medicine who state that there is no evidence supporting the effectiveness of HP are clearly wrong. It is not essential to rely only on randomised clinical trials (RCTs) to provide evidence, and in fact the findings of many RCTs are shown to be questionable over time (e.g. drugs such as Vioxx that were tested in RCTs, then later withdrawn from use because of side-effects not discovered or acknowledged during the RCTs).
Thus homoeopaths can confidently say that HP provides a definite level of protection against targeted infectious diseases, which is not 100%, but which is comparable to that of vaccines.
The Safety of Homoeoprophylaxis
Homoeopathic medicines are usually prepared using a series of dilutions and succussions (firm striking of the container holding the liquid remedy against a firm surface). The remedies are called “potencies” because at each stage they become energetically stronger. After the 12c potency, no molecules of the original substance remain, yet the remedy is energetically stronger. Pharmaceutical advocates cannot understand this, because their paradigm forces them to believe that as the number of molecules of a substance decreases in a medicine, the medicine becomes weaker. This is true if the kinetic energy of the succussion is not correctly applied, and a simple dilution only is prepared. But we are making much more than a simple dilution.
Doctors agree that homoeopathic potencies cannot be toxic, and so physical safety is not an issue. However, some homoeopaths have expressed concerns over the years as to whether the long-term use of the remedies in my HP program is energetically safe. Many people who are not bound to the pharmaceutical paradigm understand that energy can produce real and tangible effects, and if misused can cause problems. One important part of my research at Swinburne was to check the long-term safety of HP.
This was done by examining 5 markers of overall wellbeing in children aged between 4 and 12 years of age – asthma, eczema, ear/hearing problems, allergies and behavioural problems. These were compared to a range of early childhood markers, including breastfeeding status, birthweight, APGAR scores, as well as to 4 possible immunisation methods – vaccination, HP, general/constitutional prevention, and no prevention at all. That gave 20 (5 x 4) possible combinations of health conditions and immunisation methods. The data was processed using Odds Ratios and Chi Squared Probability tests.
Once again, the full results are reported in detail elsewhere (8), but the main findings are as follows:

1. In 19 of the 20 possible measures of health, vaccinated children were less healthy than other children, usually by a significant amount (the 1 measure favouring vaccination was not statistically significant). The most dramatic single finding was that vaccinated children have a 15 times greater chance of becoming asthmatic than children using HP, with P>99%, a highly statistically significant finding.
2. Children using HP were generally at least as healthy (and often more healthy) as children who used constitutional/general immunisation or no immunisation at all. The HP group were not exclusively from people who were extremely health conscious. Regularly, parents using my HP program say that it is their first introduction to homoeopathy and to natural medicine in general.
3. Parental estimates of general wellbeing were very high in the HP group – at least as high as in other groups.
4. Not all HP programs give consistent results. When comparing children using my HP program to those using other HP programs, the levels of both effectiveness and safety were lower in the group using other programs. So it is advisable to check the basis of a HP program before committing to it. Programs using daily doses of low potencies provide less effective long-term prevention than programs using infrequent doses of (appropriately selected) high potencies.
   We may conclude from the parts of my data which were statistically significant (P?95%), that HP is associated with an improvement in general health, compared to other immunisation methods (as well as no immunisation at all), and that this figure is significantly better when compared to vaccinated children. Therefore we may conclude that the evidence suggests that the use of an appropriate long-term HP program does not lessen the health of children, and evidence suggests that it may in fact assist the maturation of the immune system by gently challenging the system in the first 5-6 years of life.
   Concluding Comments
   What began as a limited study 20 years ago has grown, for me, into an ongoing attempt to make parents, as well as health professionals, aware of the wonderful opportunity that homoeoprophylaxis offers to provide protection against target infectious diseases, without risking the long-term health of their children. It may be safely used by adults.
   Not every infectious disease is a dire threat to a healthy infant. I personally don’t believe that immunisation against every infectious disease is essential. But I do believe that the right to choose which diseases should be prevented should belong to the parents of each child. We can confidently say to parents that they can provide a high (but not complete) level of protection against targeted diseases, without risk, by using an appropriate HP program.
   We can also say to those within the pharmaceutical industry who disparage HP as being untested and uncertain – take the time to study the facts available. Criticism without facts is the anthesis of the true scientific method, yet it is the response we continually get from pharmaceutical medicine when it comes to HP.
   I concluded my doctoral thesis by saying that “a national immunisation system, where both vaccination and HP were available to parents, would increase the national coverage against targeted infectious diseases, and reduce the incidence of some chronic health conditions, especially asthma” (9). The data is unambiguous, and it is time that those who run the health services of this country get serious about long-term health, and fully support the use of the best of what natural medicine in general, and homoeopathic medicine in particular, has to offer.
   Vaccines offer a level of protection against targeted infectious diseases, but involve a long-term risk that has never been adequately measured. Evidence shows that vaccination is a factor in the increase in asthma (and other chronic diseases) shown earlier. We can achieve a comparable level of protection, without this risk, by using an appropriate long-term HP program. It’s time that those parents who search for facts to inform themselves before vaccinating are encouraged, and not attacked by agents of the pharmaceutical industry. It’s time that parents are supported in their choice of immunisation method, for the benefit of their own children and of the entire community.
   Footnotes
   1 Golden I. Vaccination – A Homoeopathic Perspective. Nature & Health. Vol 7. No.3. Sept 1986, pages 67-70.
   2 Hahnemann S. The Cure and Prevention of Scarlet Fever. 1801. Republished in Lesser Writings. B Jain Publishers, New Delhi; pp. 369-385.
   3 Golden I. Homoeoprophylaxis – A Practical and Philosophical Review. 2001. Isaac Golden Publications, Daylesford, Australia. 3rd edition.
   4 Mroninski C, Adriano E, Mattos G. Meningococcinum: Its protective effect against meningococcal disease. Homoeopathic Links Winter, 2001. Vol 14(4); pp. 230-4.
   5 National Health and Medical Research Council (NH&MRC). The Australian Immunisation Handbook, 8th Edition. 2003. Commonwealth of Australia, Canberra.
   6 Golden I. Homoeoprophylaxis – A Fifteen Year Clinical Study. 2004. Isaac Golden Publications. Daylesford.
   7 Golden I. Vaccination and Homoeoprophylaxis – A Review of Risks and Alternatives, 6th edition. 2005. Isaac Golden Publications. Daylesford.
   8 Golden I. Homoeoprophylaxis – A Fifteen Year Clinical Study. 2004. Isaac Golden Publications. Daylesford.
   9 Golden I. The Potential Value of Homoeoprophylaxis in the Prevention of Infectious Diseases, and the Maintenance of General Health in Recipients. 2005. Swinburne University Press, Melbourne.
   About the Author…
   Dr Isaac Golden has been in homoeopathic practice since 1984. He has written 8 books on homoeopathic topics and currently consults in Gisborne, Victoria. Since 1990, he has been Principal of the A.C.H.H., a correspondence college teaching homoeopathy and has recently been appointed as Adjunct Professor of Homoeopathy at the Australian College of Natural Medicine. He is a world authority on the use of homoeoprophylaxis, and has completed the world’s largest long term trial of the method. He was awarded a PhD from Swinburne University in 2004 as a result of the research on HP he has undertaken over the last 20 years. Click here for further information about Dr Golden and his publications.
   Other Resources
   Disease Prevention and Homeopathy (Rudi Verspoor)
   Do We Need To Protect Against Infectious Diseases, And If We Do, How Can We Maximise Protection With Limited Long-Term Risks? (Isaac Golden)
   Homeoprophylaxis: A Fifteen-Year Clinical Study – A Statistical Review of the Efficacy, Safety of Long-Term Homeoprophylaxis, 2004 (Isaac Golden)
   Homeoprophylaxis – A Practical And Philosophical Review, 4th ed, 2007 (Isaac Golden)
   The Prevention of Epidemic Diseases By Homeopathy – Part 1, The Origin of Homeoprophylaxis (Simillimum)
   Vaccination and Homeoprophylaxis (Isaac Golden)
   Homeoprophylaxis (Isaac Golden)

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